Calcium: magnesium consumption ratio and you may colorectal carcinogenesis, comes from the new prostate, lung, colorectal, and you can ovarian malignant tumors testing demonstration

Calcium: magnesium consumption ratio and you may colorectal carcinogenesis, comes from the new prostate, lung, colorectal, and you can ovarian malignant tumors testing demonstration

I lined up to evaluate the latest relationships between calcium supplements and differing degree away from colorectal carcinogenesis and you can if or not these types of relationships is changed by calcium so you can magnesium (Ca:Mg) proportion.

Overall performance

Calcium intake did not show a dose–response association with incident adenoma of any size/stage (P-development = 0.17), but followed an inverse trend when restricted to synchronous/advanced adenoma cases (P-trend = 0.05). This inverse trend was mainly in participants with Ca:Mg ratios between 1.7 and 2.5 (P-trend = 0.05). No significant associations were observed for metachronous adenoma. Calcium intake was inversely associated with CRC (P-trend = 0.03); the association was primarily present for distal CRC (P-trend = 0.01). The inverse association between calcium and distal CRC was further modified by the Ca:Mg ratio (P-communications < 0.01); significant dose–response associations were found only in participants with a Ca:Mg ratio between 1.7 and 2.5 (P-trend = 0.04). No associations for calcium were found in the Ca:Mg ratio above 2.5 or below 1.7. Nastavi čitati “Calcium: magnesium consumption ratio and you may colorectal carcinogenesis, comes from the new prostate, lung, colorectal, and you can ovarian malignant tumors testing demonstration”